职 务：必威BETWAY官网全球健康学系主任

    betway中文官网全球健康研究中心副主任

招生专业：劳动卫生与环境卫生学(博士)

       流行病与卫生统计学(学硕)

       公共卫生硕士(专硕)

个人简介：

向浩，教授，博士生导师，betway中文官网珞珈青年学者。主要研究方向为环境流行病学和全球健康学。近5年来，主持国家自然科学基金1项，美国梅琳达-盖茨基金会项目2项(“在中国实现健康相关可持续发展目标：开发循证政策行动建议”和“完善中国医疗保险制度研究”)，以及国家卫生健康委和湖北省卫健委项目总计15项，累计到账经费281万元。以第一和通讯作者发表SCI/SSCI论文50余篇，12篇发表于Journal of Hazardous Materials、Environment International和Environmental Health and Preventive Medicine等SCI/SSCI 1区杂志，14篇发表于Environmental Pollution、Environmental Research和Atmospheric Environment等SCI/SSCI 2区杂志，累计被引用557次，ESI高被引论文1篇，H指数为16。参编的学术专著“实现健康中国2030目标——基于实证的研究”，由卫生健康领域的权威出版社“人民卫生出版社”出版。2018年主笔的咨询报告《关于疫苗风险点防控的对策建议》和《我省专家对加强疫苗监督管理的工作建议》分别被中共中央办公厅采纳和湖北省委书记批示，新冠肺炎疫情期间参与撰写的6项咨询报告获中央和省级领导批示，其中《关于降低武汉市新冠肺炎病死率的建议》获得李克强总理的肯定性批示。

科研方面，长期围绕环境健康和健康中国开展研究，主要在三个领域推进创新：(1) 空气污染与慢性病：基于遥感信息技术和人群健康大数据，构建环境健康风险评估模型，在国内首次系统评估PM1，PM2.5和NO2等空气污染物对高血压、糖尿病和血脂异常等慢性疾病的影响，研究结果为完善大气污染的精准防控政策提供重要依据；(2) 空气污染与母婴健康：构建PM2.5、PM10和NO2等空气污染物的个体暴露模型，明确空气污染是早产和低出生体重等多种母婴疾病的重要危险因素，研究结果先后被Nature (IF=42.779)，Lancet Global Health (IF=21.597)和Environment Health Perspectives (IF=8.341)等国际权威期刊累计引用136次，在该研究领域产生较大的国际影响；(3) 健康中国的实现策略：围绕“健康中国2030规划纲要”的相关目标，深入分析实现健康中国过程中可能面临的主要挑战，并就儿童营养、妇幼和生殖健康、结核病和慢性病四大重点领域展提出相应对策建议，是国内首个基于循证数据全面深入研究健康中国实现的策略研究，研究结果为推进落实健康中国2030提供理论参考和循证依据。

学术兼职包括国家自然科学基金项目通讯评审专家，教育部学位中心论文评阅专家，中国全球健康大学联盟（CCUGH）第三届理事会副主席，中国全球卫生网络理事，中华预防医学会全球卫生分会委员，湖北省预防医学会理事，湖北省预防医学会流行病学专业委员会委员。担任BMC Public Health (SSCI 2区期刊，IF=2.521)的副主编，Global Health Research and Policy和Global Health Journal的编委，中华疾病预防控制杂志(CSCD)编委，气候变化研究进展(CSCD)编委，ES&T, Environmental International, Environment Research等30多个期刊的审稿人。

一、教育背景

2004–2009，华中科技大学，必威BETWAY官网流行病与卫生统计学系，博士

1999–2004，华中科技大学，必威BETWAY官网预防医学专业，学士

二、工作经历

2020/11至今,必威BETWAY官网，教授，博士生导师

2013/11-2020/10，betway中文官网健康学院，副教授，硕士生导师

2011/08–2012/09，美国匹兹堡大学，必威BETWAY官网流行病学系，访问学者

2009/07–2013/10，必威BETWAY官网，流行病与卫生统计学系，讲师

三、主要研究方向：

1. 环境流行病学：大气污染物对慢性非传染性疾病的影响及机制研究。

2. 全球健康学：中国贫困农村地区医疗保障及卫生体系研究。

四、代表性课题

1. 盖茨基金会项目“在中国实现健康相关可持续发展目标：开发循证政策行动建议(Achieving Health SDGs in China: Developing Evidence-based Policy Options for Action) ”(OPP1148464), 起止时间：2016.10-2018.10；

2. 盖茨基金会项目“基于国内外比较分析完善中国医疗保险体系”(OPP1199760), 起止时间：2019.1-2019.12；

3. 国家自然科学基金青年基金项目“BER通路基因miRNA结合位点基因多态性与结直肠癌易感性的关联及功能研究”(81402743)， 起止时间：2015.1-2017.12；

4. 湖北省自然科学基金面上项目“CircRNA-MYLK结合miR-19调控PTEN基因在结直肠癌中作用及机制研究”(No.2018CFB634)，起止时间：2018.1-2019.12

5. 湖北省卫生计生委青年人才项目“NER基因MiRNA结合位点多态性与结直肠癌易感性的关联研究”(WJ2015Q023) ，起止时间：2015.3-2017.3；

6. 美国中华医学基金会(CMB)教学研究项目“基于胜任力的全球健康人才培养实践和理论探索”（13-134），起止时间：2013.01-2017.12

7. 中央高校基本科研项目(自主科研学科交叉类) “基于遥感的细颗粒物暴露对心血管疾病急性效应的影响研究”(2042016kf0165) , 起止时间：2016.1-2017.12

8. betway中文官网珞珈青年人才项目，微小RNA与结直肠癌易感性的关联及机制研究，时间：2016.1-2018.12

9. 湖北省高等学校省级教学改革研究项目 “基于HEdPERF量表的全球健康本科专业教学质量评价研究”(2018JG064), 起止时间：2018.7-2020.7

10. 湖北省高等学校省级教学改革研究项目 “基于德尔菲法的全球健康学专业课程体系评价指标的构建”，起止时间：2015.1-2016.12

五、代表性论文 ：

1.Jiang J, Chen G, Li B, Li N, Liu F, Lu Y, Guo Y, Li S, Chen L, Xiang H*. Associations of residential greenness with hypertension and blood pressure in a Chinese rural population: a cross-sectional study. Environ Sci Pollut Res Int. (IF:3.056) 2021 May 14. doi: 10.1007

2.Liu F, Chen X, Liu Y, Niu Z, Tang H, Mao S, Li N, Chen G, Xiang H*. Serum cardiovascular-related metabolites disturbance exposed to different heavy metal exposure scenarios. J Hazard Mater (IF: 9.038). 2021 Aug 5;415:125590. doi: 10.1016/j.jhazmat.2021.125590. 

3.Yan Y, Chen X, Guo Y, Wu C, Zhao Y, Yang N, Dai J, Gong J, Xiang H*. Ambient air pollution and cerebrovascular disease mortality: an ecological time-series study based on 7-year death records in central China. Environ Sci Pollut Res Int. (IF:3.056). 2021 Jun;28(21):27299-27307. doi: 10.1007/s11356-021-12474-z.

4.Niu Z, Liu F, Yu H, Wu S, Xiang H*. Association between exposure to ambient air pollution and hospital admission, incidence, and mortality of stroke: an updated systematic review and meta-analysis of more than 23 million participants. Environ Health Prev Med. (IF:2.710) 2021 Jan 26;26(1):15. doi: 10.1186/s12199-021-00937-1.

5.Li R, Chen G, Jiao A, Lu Y, Guo Y, Li S, Wang C, Xiang H*. Residential Green and Blue Spaces and Type 2 Diabetes Mellitus: A Population-Based Health Study in China. Toxics. (IF:3.271) 2021 Jan 16;9(1):11. doi: 10.3390/toxics9010011.

6.Niu Z, Liu F, Li B, Li N, Yu H, Wang Y, Tang H, Chen X, Lu Y, Cheng Z, Liu S, Chen G, Zhang Y, Xiang H*. Acute effect of ambient fine particulate matter on heart rate variability: an updated systematic review and meta-analysis of panel studies. Environ Health Prev Med. (IF:2.710) 2020 Dec 1;25(1):77. doi: 10.1186/s12199-020-00912-2.

7.Tang H, Cheng Z, Li N, Mao S, Ma R, He H, Niu Z, Chen X, Xiang H*. The short- and long-term associations of particulate matter with inflammation and blood coagulation markers: A meta-analysis. Environment Pollution. (IF: 5.714) 2020 Dec;267:115630. doi: 10.1016/j.envpol.2020.115630.

8.Xie Y#, Xiang H#, Di N, Mao Z, Hou J, Liu X, Huo W, Yang B, Dong G, Wang C, Chen G, Guo Y, Li S. Association between residential greenness and sleep quality in Chinese rural population. Environment International. (IF: 7.943) 2020 Dec;145:106100. doi: 10.1016/ j.envint. 2020.106100.

9.Xiaolu Chen , Feifei Liu, Zhiping Niu, Shuyuan Mao, Hong Tang, Na Li, Gongbo Chen, Suyang Liu, Yuanan Lu, Xiang Hao*. The Association Between Short-Term Exposure to Ambient Air Pollution and Fractional Exhaled Nitric Oxide Level: A Systematic Review and Meta-Analysis of Panel Studies. Environmental Pollution (IF: 5.714), 2020 Jun 6;265(Pt A):114833. doi: 10.1016/j.envpol.2020.114833.

10.Mao Shuyuan#, Li Shanshan#, Wang Chongjian, Liu Yisi, Li Na, Liu Feifei, Huang Shuqing, Liu Suyang, Lu Yuanan, Mao Zongfu, Huo Wenqian, Chen Gongbo*, Xiang Hao*, Guo Yuming. Is long-term PM1 exposure associated with blood lipids and dyslipidemias in a Chinese rural population? Environment International (IF: 7.943), 2020, 138:105637

11.Li Na#, Chen Gongbo#, Liu Feifei, Mao Shuyuan, Liu Yisi, Liu Suyang, Mao Zongfu, Lu Yuanan, Wang Chongjian, Guo Yuming, Xiang Hao*, Li Shanshan. Associations between long-term exposure to air pollution and blood pressure and effect modifications by behavioral factors. Environmental Research (IF: 5.026), 2020, 182: 109109.

12.Jiayuan Hao, Zhiyi Yang, Shuqiong Huang, Wenwen Yang, Zhongmin Zhu, Liqiao Tian, Yuanan Lu, Hao Xiang*, Suyang Liu*. Acute effects of air pollution on the incidence of hand, foot, and mouth disease in Wuhan, China. Atmospheric Environment (IF: 4.012), 2020, 225: 117358.

13.WenyuanYu,Suyang Liu, JunfengJiang, GongboChen, HuijuanLuo, YuanshanFu, LinglingXie, BaojingLi, NaLi, ShuChen, Hao Xiang*, Shenglan Tang. Burden of ischemic heart disease and stroke attributable to exposure to atmospheric PM2.5 in Hubei province, China Atmospheric Environment (IF: 4.012), 2020, 15 January,Volume 221, 117079

14.Hao Jiayuan, Yang Zhiyi, Yang Wenwen, Huang Shuqiong, Tian Liqiao, Zhu Zhongmin, Lu Yuanan, Xiang Hao*, Liu Suyang*. Impact of Ambient Temperature and Relative Humidity on the Incidence of Hand-Foot-Mouth Disease in Wuhan, China. International Journal of Environmental Research and Public Health (IF: 2.468), 2020, 17(2): 428.

15.Liu F, Guo Y, Liu Y, Chen G, Wang Y, Xue X, Liu S, Huo W, Mao Z, Hou Y, Lu Y, Wang C, Xiang H*, Li S. Associations of long-term exposure to PM1, PM2.5, NO2 with type 2 diabetes mellitus prevalence and fasting blood glucose levels in Chinese rural populations. Environment International. (IF: 7.943) 2019:105213. doi:10.1016/j.envint.2019.105213.

16.Li N, Chen G, Liu F, Mao S, Liu Y, Hou Y, Lu Y, Liu S, Wang C∗, Xiang H∗, Guo Y, Li S. Associations of long-term exposure to ambient PM1 with hypertension and blood pressure in rural Chinese population: The Henan rural cohort study. Environment International. (IF: 7.943) 2019 Apr 26;128:95-102. doi: 10.1016/j.envint.2019.04.037.

17.Mao S, Chen G, Liu F, Li N, Wang C, Liu Y, Liu S, Lu Y, Xiang H*, Guo Y, Li S. Long-term effects of ambient air pollutants to blood lipids and dyslipidemias in a Chinese rural population. Environmental Pollution. (IF: 5.714) 2019 Oct 18:113403. doi: 10.1016/j.envpol. 2019. 113403. 

18.Chen G#, Xiang H#, Mao Z, Huo W, Guo Y, Wang C, Li S. Is long-term exposure to air pollution associated with poor sleep quality in rural China? Environment International. (IF: 7.943)2019 Dec;133(Pt B):105205. doi: 10.1016/j.envint.2019.105205

19.Hao J, Yang Z, Huang S, Yang W, Zhu Z, Tian L, Lu Y, Xiang H∗, Liu S∗. The association between short-term exposure to ambient air pollution and the incidence of mumps in Wuhan, China: A time-series study. Environment Research (IF: 5.026), 2019 Oct;177: 108660. Doi:0.1016/ j.envres.2019. 108660

20.Liu F, Chen G, Huo W, Wang C, Liu S, Li N, Mao S, Hou Y, Lu Y, Xiang H∗. Associations between long-term exposure to ambient air pollution and risk of type 2 diabetes mellitus: A systematic review and meta-analysis. Environment Pollution. (IF: 5.714) 2019 Sep;252(Pt B):1235-1245. doi: 10.1016/j.envpol.2019.06.033. Epub 2019 Jun 13.

21.Guan L, Gao P, Liu S, Liu Y, Li X, Liu F, Mao Z, Lu Y, Xiang H*. Development of a global health bachelor curriculum in China: a Delphi study. BMJ Open. 2019 Jan 3;9(1):e023893. doi: 10.1136/bmjopen-2018-023893.

22.Qing Huang, Yunzhao Ren, Yisi Liu, Suyang Liu, Feifei Liu, Xiangyu Li, Baojing Li,Yitan Hou, Yuanan Lu, Shiyue Li, Hong Yan∗, Hao Xiang∗ Associations of gestational and early life exposure to air pollution with childhood allergic rhinitis. Atmospheric Environment 2019 200: 190-196

23.Yunzhao Ren, Xing Yao, Yisi Liu, Suyang Liu, Xiao Li, Qing Huang, Feifei Liu, Na Li, Yuanan Lu, Zhanpeng Yuan, Shiyue Li, Hao Xiang* Outdoor air pollution pregnancy exposures are associated with behavioral problems in China’s preschoolers. Environmental Science and Pollution Research. 2019 Jan;26(3):2397-2408. doi: 10.1007 

24.Yu W, Jiang J, Xie L, Li B, Luo H, Fu Y, Chen S, Wu C, Xiang H*, Tang S. Mortality Trends in Colorectal Cancer in China During 2000-2015: A Joinpoint Regression and Age-Period-Cohort Analysis. Preventing Chronic Disease. 2018 Dec 13;15:E156. doi: 10.5888/ pcd15.180329.

25.Chen S, Guo L, Wang Z, Mao W, Ge Y, Ying X, Fang J, Long Q, Liu Q, Xiang H, Wu C, Fu C, Dong D, Zhang J, Sun J, Tian L, Wang L, Zhou M, Zhang M, Qian M, Liu W, Jiang W, Feng W, Zeng X, Ding X, Lei X, Tolhurst R, Xu L, Wang H, Ziegeweid F, Glenn S, Ji JS, Story M, Yamey G, Tang S. Current situation and progress toward the 2030 health-related Sustainable Development Goals in China: A systematic analysis. PLoS Med. 2019 Nov 19;16(11):e1002975. doi: 10.1371/journal.pmed.1002975. 

26.Liu Xiaotian #, Tu Runqi#, Qiao Dou, Niu Miaomiao, Li Ruiying, Mao Zhenxing, Huo Wenqian, Chen Gongbo, Xiang Hao, Guo Yuming, Li Shanshan*, Wang Chongjian*. Association between long-term exposure to ambient air pollution and obesity in a Chinese rural population: The Henan Rural Cohort Study. Environmental Pollution (IF: 5.714), 2020, 260:114077.

27.Hou Jian, Liu Xiaotian, Tu Runqi, Dong Xiaokang, Zhai Zhihan, Mao Zhenxing, Huo Wenqian, Chen Gongbo, Xiang Hao, Guo Yuming, Li Shanshan*, Wang Chongjian*. Long-term exposure to ambient air pollution attenuated the association of physical activity with metabolic syndrome in rural Chinese adults: A cross-sectional study. Environment International (IF: 7.943), 2020, 136:10545

28.Pan Gao, Hao Xiang*, Suyang Liu, Yisi Liu, Shengjie Dong, Feifei Liu, Wenyuan Yu, Xiangyu Li, Li Guan, Yuanyuan Chu, Zongfu Mao, Shu Chen, Shenglan Tang. Evaluation of a consulting training course for international development assistance for health. BMC Medical Education, 2018, 18:234

29.Li X, Liu Y, Liu F, Wang Y, Yang X, Yu J, Xue X, Jiao A, Lu Y, Tian L, Deng S, Xiang H*. Analysis of short-term and sub-chronic effects of ambient air pollution on preterm birth in central China. Environmental Science and Pollution Research, 2018 Jul; 25(19): 19028- 19039.

30.Liu, F, Zhang F, Li X, Liu Q, Liu W, Song P, Qiu Z, Dong Y, Xiang H*. Prognostic role of miR-17-92 family in human cancers: evaluation of multiple prognostic outcomes. Oncotarget. 2017 Jul 8;8(40):69125-69138. doi: 10.18632/oncotarget.19096.

31.Li X, Huang S, Jiao A, Yang X, Yun J, Wang Y, Xue X, Chu Y, Liu F, Liu Y, Ren M, Chen X, Li N, Lu Y, Mao Z, Tian L, Xiang H*. Association between ambient fine particulate matter and preterm birth or term low birth weight: An updated systematic review and meta-analysis. Environmental Pollution. 2017 Apr 27. pii: S0269-7491(16)32550-7. doi: 10.1016

32.Meng Ren, Na Li, Zhan Wang, Yisi Liu, Xi Chen, Yuanyuan Chu, Xiangyu Li, Zhongmin Zhu, Liqiao Tian, Hao Xiang*. The Short-term Effect of Air Pollutants on Respiratory Diseases Mortality in Wuhan, China: Comparison of Time Series and Case-crossover Analysis. Scientific Report (IF: 4.011)2017, 7:40482

33.Yisi Liu, Xi Chen, Shuqiong Huang, Liqiao Tian, Yuan’an Lu, Yan Mei, Meng Ren, Na Li, Li Liu and Hao Xiang*. Association between Air Pollutants and Cardiovascular Disease Mortality in Wuhan, China. Int J Environ Res Public Health. 2015, 12, 3506-3516.

34.Feifei Liu, Lijing Yan, Zhan Wang, Yuanan Lu, Yuanyuan Chu, Xiangyu Li, Yisi Liu, Dongsheng Rui, Shaofa Nie, Hao Xiang*. Metformin therapy and risk of colorectal adenomas and colorectal cancer in type 2 diabetes mellitus patients: A systematic review and meta-analysis. Oncotarget Dec 1. doi: 10.18632/oncotarget.13762.

35.Feifei Liu, Keith Dear, Lei Huang, Li Liu, Yun Shi, Shaofa Nie, Yisi Liu, Yuanan Lu, Hao Xiang*. Association between microRNA-27a rs895819 polymorphism and risk of colorectal cancer: A meta-analysis . Cancer Genetics 2016(209):388–394

36.Yuanyuan Chu, Yisi Liu, Yuanan Lu, Lichen Yu, Hanson Lu, Yulin Guo, Fengfeng Liu, Yanyan Wu, Zongfu Mao, Meng Ren, Na Li, Xi Chen, Hao Xiang*. Propensity to Migrate and Willingness to Pay Related to Air Pollution among Different Populations in Wuhan, China. Aerosol and Air Quality Research. 2017, 17:752-760, doi: 10.4209/aaqr.2016.05.0178

37.Guo Y, Liu F, Lu Y, Mao Z, Lu H, Wu Y, Chu Y, Yu L, Liu Y, Ren M, Li N, Chen X, Hao Xiang*. Factors Affecting Parent's Perception on Air Quality-From the Individual to the Community Level. Int J Environ Res Public Health. 2016, 13(5). 

38.Yuanyuan Chu, Yisi Liu, Xiangyu Li, Zhiyong Liu, Hanson Lu, Yuanan Lu, Zongfu Mao, Xi Chen, Na Li, Meng Ren, Feifei Liu, Liqiao Tian, Zhongmin Zhu, Hao Xiang*. A Review on Predicting Ground PM2.5 Concentration Using Satellite Aerosol Optical Depth. Atmosphere 2016, 7, 129.

39.Ying Xia, Jiafa Liu, Tingming Shi, Hao Xiang*, Yongyi, Bi*. Prevalence of Pneumoconiosis in Hubei, China from 2008 to 2013. Int J Environ Res Public Health. 2014, 11(9): 8612-8621. 

40.Xu Z, Tong S, Cheng J, Crooks JL, Xiang H, Li X, Huang C, Hu W. Heatwaves and diabetes in Brisbane, Australia: a population-based retrospective cohort study. International Journal of Epidemiology. 2019 Mar 29. pii: dyz048. doi: 10.1093/ije/dyz048.

41.Tianhao Zhang, Zhongmin Zhu, Wei Gong, Hao Xiang, Ying Li and Zhenzhen Cui. Characteristics of Ultrafine Particles and Their Relationships with Meteorological Factors and Trace Gases in Wuhan, Central China. Atmosphere 2016, 7, 96.

42.Tianhao Zhang, Zhongmin Zhu, Wei Gong, Hao Xiang and Ruimin Fang. Characteristics of Fine Particles in an Urban Atmosphere-Relationships with Meteorological Parameters and Trace Gases Int. J. Environ. Res. Public Health 2016, 13, 807.

43.Xiang H, Mertz KJ, Arena VC, Brink LL, Xu X, Bi Y, Talbott EO. Estimation of short-term effects of air pollution on stroke hospital admissions in Wuhan, China. PLoS One. 2013, 12, 8(4): e61168.